
Pharmaceutical Materials Coarse Crusher
Efficiently crush various medicinal raw materials to the required fineness
Fineness: 10-600 mesh
Output: 5-3000kg/h
Material: 304 or 316L stainless steel
What is Pharmaceutical Materials Coarse Crusher?
Pharmaceutical Materials Coarse Crusher is a precision crushing equipment specially developed for the pharmaceutical industry. It uses advanced crushing technology and can efficiently crush various pharmaceutical raw materials to the required fineness. Our equipment series covers small laboratory machines to large industrial production machines, which can meet the crushing needs of users of different sizes.
What types of Pharmaceutical Materials Coarse Crusher are there?
Pharmaceutical Materials Coarse Crusher is divided into four categories according to the crushing principle and application scenario: mechanical, airflow, low temperature and aseptic crusher. Each category is designed for raw materials with different characteristics and has its own unique crushing principle and application advantages.
Crusher type | Crushing principle | Applicable raw materials | Typical applications | Core advantages |
Mechanical Pharmaceutical Materials Coarse Crusher | Gear type: fixed gear ring and rotating gear disc run relative to each other at high speed, impact, shear, and collide to crush Hammer type: movable hammer and fixed ring move relative to each other Knife type: rotating blade and fixed gear ring shear | Ordinary Chinese medicinal materials, chemical API crystals, granular materials | Chinese medicinal materials such as ginseng and Panax notoginseng; crystalline APIs such as sucrose and salt | Applicable to a variety of common raw materials, with different structural designs according to the characteristics of the raw materials |
Airflow Pharmaceutical Materials Coarse Crusher | The high-speed airflow energy is used to cause strong impact friction between drug particles, and the double-screw feeding system ensures stable feeding of materials with poor fluidity | High value-added APIs, hormone drugs, and ultra-fine powder materials | Hormonal drugs such as dexamethasone; poorly soluble APIs that need to improve bioavailability | Can achieve ultra-fine grinding to meet the processing needs of special materials |
Low-temperature Pharmaceutical Materials Coarse Crusher Crusher | Crushing in a deep cold environment with a minimum temperature of -70℃ | Thermosensitive APIs, easily oxidizable materials, medicinal materials containing volatile ingredients, medicinal materials containing oily or sticky ingredients | Ganoderma lucidum spore powder, vitamins, antibiotic APIs, Chinese medicinal materials containing volatile oils | Prevent damage to heat-sensitive ingredients and maintain drug efficacy |
Sterile Pharmaceutical Materials Coarse Crusher | Sterile design that fully complies with GMP requirements, can be cleaned and sterilized online, polished inner cavity without dead angles, and special structure ensures no temperature rise | Sterile APIs, injection-grade products, biological products | Sterile antibiotic APIs, freeze-dried powder injections, biological preparations | Meet the requirements of sterile production and avoid cross contamination |
What are the advantages of Pharmaceutical Materials Coarse Crusher?
Medical grade material: The material contact part of the equipment is made of 304 or 316L stainless steel, with special polishing treatment, acid and alkali resistance, strong oxide resistance, and fully meets the GMP clean requirements
Low temperature crushing: The unique structural design cooperates with external cold source refrigeration, and the temperature of the crushing chamber can be maintained at 10-20℃, which is particularly suitable for heat-sensitive APIs
Dust-free operation: The fully enclosed design is equipped with a dust removal system to achieve dust-free crushing in the clean workshop and protect the health of operators
Adjustable fineness: By replacing different mesh screens, the crushing fineness can be freely adjusted within the range of 10-500 mesh
What is the principle of Pharmaceutical Materials Coarse Crusher?
Pharmaceutical Materials Coarse Crusher mainly achieves crushing through two principles: mechanical and airflow. In terms of mechanical crushing, the toothed crusher relies on the relative movement between the fixed gear ring and the high-speed rotating gear disc to crush the medicinal raw materials under the action of impact, shear, collision and friction; the hammer crusher uses a high-speed rotating hammer to hit the raw materials on the fixed ring, and crushes them after multiple impacts and frictions. The principle of airflow crushing is that in the airflow crusher, compressed air or other gases are accelerated through the nozzle to form a high-speed airflow beam. After the medicinal raw materials enter, strong impact and friction occur between the particles and between the particles and the airflow, so that they are crushed into fine powder. This method is particularly suitable for obtaining ultra-fine powders.
Pharmaceutical Materials Coarse Crusher Parameters
Laboratory type pharmaceutical grinder
Parameters | KCWS-10 | KCWS-20 | J-20 air flow mill |
Voltage (V) | 220 | 220 | 220 |
Power (KW) | 0.75 | 1.5 | 1.2 |
Volume (mm) | 320×450×650 | 600×600×1100 | 800×600×1200 |
Weight (Kg) | 42 | 80 | 150 |
Output (Kg/h) | 5-10 | 15-30 | 0.5-100g/h |
Fineness (mesh) | 10-120 | 10-120 | d100<5-10μm |
Feed particle size (mm) | <5 | <5 | <1 |
Discharge particle size (μm) | 125-1200 | 125-1200 | 1-10 |
Production type medicinal pulverizer
Parameters | KCL-300 | KCL-400 | J-100 air flow pulverizer |
Voltage (V) | 380 | 380 | 380 |
Power (KW) | 7 | 12.5 | 15 |
Volume (mm) | 1600×800×1800 | 2000×900×1800 | 2500×1200×2000 |
Weight (Kg) | 600 | 700 | 1200 |
Output (Kg/h) | 30-150 | 50-300 | 0.5-7.5kg/h |
Fineness (mesh) | 60-120 | 60-120 | 99%<2-3μm |
Feed particle size (mm) | <10 | <10 | <3 |
Discharge particle size (μm) | 125-250 | 125-250 | 1-5 |
Special Purpose Pulverizer
Parameters | MSM Aseptic Pulverizer | Vibration Pulverizer | Fluidized Bed Pulverizer |
Voltage (V) | 380 | 220/380 | 380 |
Power (KW) | 5.5 | 3 | 7.5 |
Output (Kg/h) | 10-50 | 5-20 | 20-100 |
Fineness (mesh) | 80-200 | 60-180 | 100-300 |
Features | Online CIP/SIP | Low noise <65dB | No mechanical contact |
What are the applications of Pharmaceutical Materials Coarse Crusher?
Pharmaceutical Materials Coarse Crusher can crush different types of drugs (chemical APIs, hormone drugs, heat-sensitive antibiotics, Chinese herbal medicines, sterile APIs), and can achieve the corresponding ideal processing effects.
Processing type | Applicable equipment | Processing drugs | Processing effect |
Chemical raw material drug crushing | KCWS series high-speed shear crusher | Aspirin, ibuprofen, vitamin C, etc. | Uniform particle size, no overheating degradation, fineness can reach 200 mesh |
Ultrafine grinding of hormone drugs | J series air flow mill | Dexamethasone, fluocinolone acetate, etc. | 100<5μm, improve bioavailability |
Heat-sensitive antibiotic treatment | KCL series low-temperature grinding system | Penicillin, cephalosporin raw materials | Temperature < 20℃, zero loss of active ingredients |
Fine processing of Chinese medicinal materials | TCM series multifunctional grinder | Ginseng, Panax notoginseng, pearl, Ganoderma lucidum, etc. | High cell wall breaking rate, sufficient release of active ingredients |
Sterile API granulation | MSM type sterile pulverizer | Freeze-dried powder injection raw materials | Comply with GMP sterility requirements and improve fluidity |