Pharmaceutical Materials Coarse Crusher

What is Pharmaceutical Materials Coarse Crusher?

The Pharmaceutical Materials Coarse Crusher is used for crushing raw materials in the pharmaceutical industry. It uses high-speed rotating blades or hammers to perform impact shearing and other operations on pharmaceutical raw materials to achieve crushing. It can crush granular and large-block pharmaceutical raw materials into a particle size that meets the requirements of subsequent processing, reducing the raw material volume, improving the efficiency of subsequent processes, and preventing large-block raw materials from damaging downstream equipment. It can crush various pharmaceutical raw materials such as roots, particles, fruits, minerals, fiber-based medicinal ingredients or chemical raw materials with a particle size of 10-150mm into coarse particles or coarse powder. The output particle size is 2-20mm and can be adjusted according to demand. The hourly processing capacity is 100-3000 kg. The entire machine is made of 304 stainless steel, which is rust-proof, anti-fouling and easy to clean.

Pharmaceutical Materials Coarse Crusher Video

What types of Pharmaceutical Materials Coarse Crusher are there?

Pharmaceutical Materials Coarse Crusher can be divided into four categories according to the type of crushed pharmaceutical raw materials and application scenarios: mechanical, airflow, cryogenic, and aseptic. The appropriate model can be selected according to the properties of the crushed pharmaceutical raw materials.

Mechanical Pharmaceutical Materials Coarse Crusher uses gear or hammer type impact, shearing, collision and other operations to crush pharmaceutical raw materials. It can be used to crush common Chinese medicinal materials, chemical raw material crystals and granular materials.

Airflow Pharmaceutical Materials Coarse Crusher: Utilizes high-speed airflow to create intense collision and friction between drug particles. The twin-screw feeding system ensures stable feeding of materials with poor fluidity. Suitable for high-value-added APIs, hormone drugs, and ultrafine powder materials, it can achieve ultrafine grinding to meet the processing needs of special materials.

Low-temperature Pharmaceutical Materials Coarse Crusher: Crush pharmaceutical raw materials in a deep-cold environment at a minimum temperature of -70°C. It can be used for heat-sensitive APIs, easily oxidized APIs, medicinal materials containing volatile components, and medicinal materials containing oily or sticky components. The low temperature can prevent heat-sensitive components from being damaged and maintain the efficacy of the medicine.

Sterile Pharmaceutical Materials Coarse Crusher: The aseptic design fully complies with GMP requirements, can be cleaned and sterilized online, has a polished inner cavity with no dead corners, and a special structure to ensure no temperature rise. It is suitable for crushing sterile APIs, injection-grade products, and biological products with sterility requirements.

What are the advantages of Pharmaceutical Materials Coarse Crusher?

The Pharmaceutical Materials Coarse Crusher is made of 304 or 316L stainless steel, polished inside and out. It is acid and alkali resistant, has strong antioxidant capabilities, is not prone to rust, and is easy to clean, effectively preventing cross-infection of pharmaceutical raw materials. It uses low-temperature crushing combined with external cooling to maintain the temperature of the crushing chamber at 10-20°C without damaging the materials, making it particularly suitable for heat-sensitive APIs. The fully enclosed structure and dust removal system directly recycle and purify the dust generated during the crushing process without polluting the environment. The crushing fineness ranges from 10-500 mesh and can be adjusted by replacing the screen to meet the crushing needs of different types of materials, with an hourly processing capacity of 3,000 kilograms.

What is the principle of Pharmaceutical Materials Coarse Crusher?

Pharmaceutical Materials Coarse Crusher mainly achieves crushing through two principles: mechanical and airflow. In terms of mechanical crushing, the toothed crusher relies on the relative movement between the fixed gear ring and the high-speed rotating gear disc to crush the medicinal raw materials under the action of impact, shear, collision and friction; the hammer crusher uses a high-speed rotating hammer to hit the raw materials on the fixed ring, and crushes them after multiple impacts and frictions. The principle of airflow crushing is that in the airflow crusher, compressed air or other gases are accelerated through the nozzle to form a high-speed airflow beam. After the medicinal raw materials enter, strong impact and friction occur between the particles and between the particles and the airflow, so that they are crushed into fine powder. This method is particularly suitable for obtaining ultra-fine powders.

 

Pharmaceutical Materials Coarse Crusher Parameters

Laboratory type pharmaceutical grinder

Parameters	KCWS-10	KCWS-20	J-20 air flow mill
Voltage (V)	220	220	220
Power (KW)	0.75	1.5	1.2
Volume (mm)	320×450×650	600×600×1100	800×600×1200
Weight (Kg)	42	80	150
Output (Kg/h)	5-10	15-30	0.5-100g/h
Fineness (mesh)	10-120	10-120	d100<5-10μm
Feed particle size (mm)	<5	<5	<1
Discharge particle size (μm)	125-1200	125-1200	1-10

Production type medicinal pulverizer

Parameters	KCL-300	KCL-400	J-100 air flow pulverizer
Voltage (V)	380	380	380
Power (KW)	7	12.5	15
Volume (mm)	1600×800×1800	2000×900×1800	2500×1200×2000
Weight (Kg)	600	700	1200
Output (Kg/h)	30-150	50-300	0.5-7.5kg/h
Fineness (mesh)	60-120	60-120	99%<2-3μm
Feed particle size (mm)	<10	<10	<3
Discharge particle size (μm)	125-250	125-250	1-5

Special Purpose Pulverizer

Parameters	MSM Aseptic Pulverizer	Vibration Pulverizer	Fluidized Bed Pulverizer
Voltage (V)	380	220/380	380
Power (KW)	5.5	3	7.5
Output (Kg/h)	10-50	5-20	20-100
Fineness (mesh)	80-200	60-180	100-300
Features	Online CIP/SIP	Low noise <65dB	No mechanical contact

What are the applications of Pharmaceutical Materials Coarse Crusher?

The Pharmaceutical Materials Coarse Crusher is primarily used for raw material pretreatment in industries such as traditional Chinese medicine slice processing, pharmaceutical production, and health product manufacturing. It crushes dried Chinese medicinal materials such as rhizomes, fruits, and minerals into ideal coarse particles or powders, providing uniformly sized coarse material for subsequent fine grinding, mixing, and granulation processes. It is also used for secondary crushing of unqualified and recycled materials in pharmaceutical production. It can also be used in conjunction with production lines for continuous coarse crushing of pharmaceutical raw materials, meeting the raw material processing needs of various dosage forms such as tablets, capsules, and powders. It can be used to crush various pharmaceutical raw materials with medium hardness and low water content, such as astragalus, licorice, hawthorn, wolfberry, vitamins, antibiotic crystals, sulfonamide block materials, gypsum, talc block materials, and plant fiber medicinal materials.

Processing type	Applicable equipment	Processing drugs	Processing effect
Chemical raw material drug crushing	KCWS series high-speed shear crusher	Aspirin, ibuprofen, vitamin C, etc.	Uniform particle size, no overheating degradation, fineness can reach 200 mesh
Ultrafine grinding of hormone drugs	J series air flow mill	Dexamethasone, fluocinolone acetate, etc.	100<5μm, improve bioavailability
Heat-sensitive antibiotic treatment	KCL series low-temperature grinding system	Penicillin, cephalosporin raw materials	Temperature < 20℃, zero loss of active ingredients
Fine processing of Chinese medicinal materials	TCM series multifunctional grinder	Ginseng, Panax notoginseng, pearl, Ganoderma lucidum, etc.	High cell wall breaking rate, sufficient release of active ingredients
Sterile API granulation	MSM type sterile pulverizer	Freeze-dried powder injection raw materials	Comply with GMP sterility requirements and improve fluidity

Pharmaceutical Materials Coarse Crusher Customer Case

Application Scenarios	Crushed Materials	Feed Particle Size	Discharge Particle Size	Production (kg/h)	Equipment Model	Remarks
Pretreatment in Traditional Chinese Medicine Decoction Factory	Drying Astragalus and Licorice Roots	≤50mm	3-5mm	200-300	CSJ-300 Coarse Crusher	Suitable for coarse crushing of rhizomes and herbs, wear-resistant
Health product raw material processing	Ganoderma lucidum slices, dried wolfberries	≤30mm	2-4mm	150-200	CSJ-200 Coarse Crusher	Low noise design to prevent material overheating
Production of traditional Chinese medicine granules	Atractylodes macrocephala, Poria cocos blocks	40mm	1-3mm	250-350	CSJ-400 coarse crusher	High output, suitable for continuous feeding

How to choose a Pharmaceutical Materials Coarse Crusher?

When selecting a Pharmaceutical Materials Coarse Crusher, consider the type of pharmaceutical raw material, feed size, output size, processing capacity, and material selection. For bulky minerals, a jaw crusher is recommended. For fibrous raw materials like botanicals, a shear crusher is recommended. For heat-sensitive chemical raw materials, a model with a cooling device is recommended to prevent thermal deterioration. Also, consider the feed size, which should be between 10 and 150 mm. For processing capacity, select a model with an hourly capacity of 10 to 50 kg for small-scale laboratories, and a smaller model for over 500 kg per hour. 304 or 316L stainless steel is recommended for corrosion resistance and easy cleaning, preventing raw material contamination.

Pharmaceutical Materials Coarse Crusher Manufacturers

Pharmaceutical Materials Coarse Crusher manufacturers manufacture a variety of equipment, including hammer, geared disc, jaw, and roller models. These range from small laboratory units to large production line units, as well as low-temperature models for heat-sensitive materials. Material-contact parts are primarily constructed of 304 or 316L stainless steel, while the body is constructed of carbon steel, complying with GMP standards. Prices range widely, from a few thousand yuan for small laboratory units to over 100,000 yuan for large explosion-proof models, depending on the model, production capacity, and configuration. Customization and additional features are available, including customized explosion-proof designs (for flammable materials), hopper and discharge port dimensions, pulse dust removal, and CIP/SIP cleaning and sterilization systems. These machines are equipped with variable frequency drive speed control, casters, and some models include safety features such as travel switches and overload protection. Interchangeable screens can also be used to adjust particle size, making them suitable for a variety of materials, including traditional Chinese medicines and chemical APIs.